HUBUNGAN DEMOGRAFI, DEPRESI, KUALITAS TIDUR DENGAN FATIGUE INTRADIALISIS PADA PASIEN GAGAL GINJAL KRONIS

Anjrah Harmoko, Diana Tri Lestari, Rusnoto Rusnoto

Abstract


Gagal ginjal kronis (PGK) merupakan masalah kesehatan masyarakat global dan nasional. Pasien gagal ginjal kronis harus melakukan hemodialisis sebagai terapi yang berdampak pada fatigue. Fatigue terjadi sekitar 70% pasien ginjal yang mengakibatkan gangguan aktivitas sehari-hari dan penurunan kapasitas kerja, keterbatasan fungsi, ketidakstabilan suasana hati, gangguan tidur, gangguan fungsi keluarga dan sosial. Tujuan penelitian untuk mengetahui hubungan demografi, depresi, kualitas tidur dengan fatigue intradialisis pada pasien gagal ginjal kronis di RS  dr. Soetarto Yogyakarta. Jenis penelitian adalah penelitian observasional, bersifat analitik korelasi dengan rancangan cross-sectional. Sampel penelitian adalah pasien gagal ginjal kronis. Teknik pengambilan sampel menggunakan teknik total sampling dengan jumlah sampel sebanyak 23 pasien. Teknik pengumpulan data variabel fatigue menggunakan kuesioner baku Chalder Fatigue Scale (CFQ), Beck Depression Inventory (BDI-II), dan kuesioner Piisburg Sleep Quality Index (PSQI). Analisis data menggunakan uji chi-square dan regresi logistik. Hasil penelitian menunjukkan ada hubungan demografi jenis kelamin (P=0,011) dan umur (P=0,035) dengan fatigue intradialisis dan tidak ada hubungan status pernikahan (P=0,360) dan penghasilan (P=0,429) dengan fatigue intradialisis. Ada hubungan depresi dengan fatigue intradialisis (P=006). Ada hubungan kualitas tidur dengan fatigue intradialisis (P=0,018). Faktor paling dominan yang mempengaruhi fatigue intradialisis adalah depresi (P=0,049, CI=0,003-2,583). Fatigue umum terjadi pada pasien yang menjalani hemodialisis dan dikaitkan dengan jenis kelamin, umur, depresi dan gangguan tidur. Dokter harus secara proaktif menyelidiki tanda-tanda kelelahan untuk menghindari dampaknya terhadap kualitas hidup pasien dengan gagal ginjal kronis.

Keywords


demografi, depresi, fatigue intradialisis, kualitas hidup

Full Text:

PDF

References


Al Naamani, Z., Gormley, K., Noble, H., Santin, O., & Al Maqbali, M. (2021). Fatigue, anxiety, depression and sleep quality in patients undergoing haemodialysis. BMC Nephrology, 22(1), 157. https://doi.org/10.1186/s12882-021-02349-3

Alshammari, B., Alkubati, S. A., Alrasheeday, A., Pasay-An, E., Edison, J. S., Madkhali, N., Al-Sadi, A. K., Altamimi, M. S., Alshammari, S. O., Alshammari, A. A., & Alshammari, F. (2024). Factors influencing fatigue among patients undergoing hemodialysis: A multi-center cross-sectional study. Libyan Journal of Medicine, 19(1), 2301142. https://doi.org/10.1080/19932820.2023.2301142

Amelia, F., Safitri, K. H., & Suwanto, S. (2021). Determinant Fatigue Pada Pasien Esrd Yang Menjalani Hemodialisis. Jurnal Keperawatan Wiyata, 2(1), Article 1. https://doi.org/10.35728/jkw.v2i1.495

Anita, D. C., & Husada, I. S. (2020). Depresi Pada Pasien Hemodialisa Perempuan Lebih Tinggi. The 11th University Research Colloquium 2020 Universitas ‘Aisyiyah Yogyakarta.

Bossola, M., Di Stasio, E., Monteburini, T., Santarelli, S., Cenerelli, S., Manes, M., Parodi, E. L., Angioletti, L., & Balconi, M. (2022). Fatigue and apathy in patients on chronic hemodialysis. Therapeutic Apheresis and Dialysis, 26(5), 932–940. https://doi.org/10.1111/1744-9987.13784

Broch, L., Flemmen, H. Ø., Simonsen, C. S., Berg-Hansen, P., Ormstad, H., Brunborg, C., & Celius, E. G. (2022). Fatigue in multiple sclerosis is associated with socioeconomic factors. Multiple Sclerosis and Related Disorders, 64, 103955. https://doi.org/10.1016/j.msard.2022.103955

Brys, A. D. H., Lenaert, B., Van Heugten, C. M., Gambaro, G., & Bossola, M. (2019). Exploring the Diurnal Course of Fatigue in Patients on Hemodialysis Treatment and Its Relation With Depressive Symptoms and Classical Conditioning. Journal of Pain and Symptom Management, 57(5), 890-898.e4. https://doi.org/10.1016/j.jpainsymman.2019.02.010

Burdelis, R. E. M., & Cruz, F. J. S. M. (2023). Prevalence and predisposing factors for fatigue in patients with chronic renal disease undergoing hemodialysis: A cross-sectional study. Sao Paulo Medical Journal, 141(5), e2022127. https://doi.org/10.1590/1516-3180.2022.0127.r1.01122022

Debnath, S., Rueda, R., Bansal, S., Kasinath, B. S., Sharma, K., & Lorenzo, C. (2021). Fatigue characteristics on dialysis and non-dialysis days in patients with chronic kidney failure on maintenance hemodialysis. BMC Nephrology, 22(1), 112. https://doi.org/10.1186/s12882-021-02314-0

Devi, E. I., Prihatiningsih, D., & Widaryati, W. (2024). Hubungan Efikasi Diri dan Perawatan Diri pada Pasien dengan Hemodialisa. Jurnal Ilmiah Kesehatan, 13(1), 1–11. https://doi.org/10.52657/jik.v13i1.2269

Dewi, L. N., & Hendrati, L. Y. (2022). Hubungan Kualitas Tidur Dengan Depresi Pada Pasien Gagal Ginjal Kronis Yang Menjalani Hemodialisis. Preventif : Jurnal Kesehatan Masyarakat, 13(2), Article 2. https://doi.org/10.22487/preventif.v13i2.373

Fotaraki, Z.-M., Gerogianni, G., Vasilopoulos, G., Polikandrioti, M., Giannakopoulou, N., & Alikari, V. (2022). Depression, Adherence, and Functionality in Patients Undergoing Hemodialysis. Cureus, 14(2), e21872. https://doi.org/10.7759/cureus.21872

Gregg, L. P., Bossola, M., Ostrosky-Frid, M., & Hedayati, S. S. (2021). Fatigue in CKD: Epidemiology, Pathophysiology, and Treatment. Clinical Journal of the American Society of Nephrology, 16(9), 1445. https://doi.org/10.2215/CJN.19891220

Halawa, A., Anggeria, E., Sitopu, R. F., Tarigan, Y. M. S., Novita, E., & Halawa, E. (2023). Pengaruh Pijatan Punggung terhadap Penurunan Kelelahan Fisik Pada Pasien Gagal Ginjal Kronis. Jurnal Ilmu Psikologi Dan Kesehatan (SIKONTAN), 1(3), Article 3. https://doi.org/10.47353/sikontan.v1i3.619

Hunter, S. K. (2014). Sex differences in human fatigability: Mechanisms and insight to physiological responses. Acta Physiologica (Oxford, England), 210(4), 768–789. https://doi.org/10.1111/apha.12234

Inayah, D. (2022). Hubungan Tingkat Kecemasan Dengan Kualitas Tidur Pasien Gagal Ginjal Kronik Yang Menjalani Hemodialisis Di Klinik Diatrans Jatiwaringin [Bachelor, Universitas Binawan]. https://repository.binawan.ac.id/2142/

Jannah, M., Kamsani, S. R., & Ariffin, N. M. (2021). Perkembangan Usia Dewasa: Tugas Dan Hambatan Pada Korban Konflik Pasca Damai. Bunayya : Jurnal Pendidikan Anak, 7(2), 114–143. https://doi.org/10.22373/bunayya.v7i2.10430

Kalantar-Zadeh, K., Jafar, T. H., Nitsch, D., Neuen, B. L., & Perkovic, V. (2021). Chronic Kidney Disease. The Lancet, 398(10302), 786–802. https://doi.org/10.1016/S0140-6736(21)00519-5

Kementerian Kesehatan RI. (2023). SKI 2023 Dalam Angka. Kementerian Kesehatan Republik Indonesia. https://www.badankebijakan.kemkes.go.id/ski-2023-dalam-angka/

Kentson, M., Tödt, K., Skargren, E., Jakobsson, P., Ernerudh, J., Unosson, M., & Theander, K. (2016). Factors associated with experience of fatigue, and functional limitations due to fatigue in patients with stable COPD. Therapeutic Advances in Respiratory Disease, 10(5), 410–424. https://doi.org/10.1177/1753465816661930

Khadija, S., Harun, S., & Setiawati, E. M. (2024). Hubungan antara fatigue dengan kualitas tidur pada pasien CKD yang Menjalani Hemodialisa di RS PKU Muhammadiyah Yogyakarta. Prosiding Seminar Nasional Penelitian dan Pengabdian Kepada Masyarakat LPPM Universitas ’Aisyiyah Yogyakarta, 2, 1352–1357.

Khusniyati, N., Yona, S., & Kariasa, I. M. (2019). Fatigue, Depresi, Terhadap Kualitas Hidup Pada Pasien Hemodialisa. Jurnal Keperawatan Terpadu (Integrated Nursing Journal), 1(2), Article 2. https://doi.org/10.32807/jkt.v1i2.30

Korin, J. M., Nugrahayu, E. Y., & Devianto, N. (2020). Hubungan Lama Menjalani Hemodialisis dengan Tingkat Depresi pada Pasien Hemodialisis di RSUD Abdul Wahab Sjahranie Samarinda. Jurnal Sains dan Kesehatan, 2(4), Article 4.

Lim, E.-J., & Son, C.-G. (2022). Comparison of Assessment Scores for Fatigue Between Multidimensional Fatigue Inventory (MFI-K) and Modified Chalder Fatigue Scale (mKCFQ). Journal of Translational Medicine, 20(1), 8. https://doi.org/10.1186/s12967-021-03219-0

Liyanage, T., Toyama, T., Hockham, C., Ninomiya, T., Perkovic, V., Woodward, M., Fukagawa, M., Matsushita, K., Praditpornsilpa, K., Hooi, L. S., Iseki, K., Lin, M.-Y., Stirnadel-Farrant, H. A., Jha, V., & Jun, M. (2022). Prevalence of chronic kidney disease in Asia: A systematic review and analysis. BMJ Global Health, 7(1), e007525. https://doi.org/10.1136/bmjgh-2021-007525

Lolowang, N. N. L., Lumi, W. M. E., & Rattoe, A. A. (2020). Kualitas Hidup Pasien Gagal Ginjal Kronis Dengan Terapi Hemodialisa. Jurnal Ilmiah Perawat Manado (Juiperdo), 8(02), Article 02. https://doi.org/10.47718/jpd.v8i01.1183

Lusiana, R., Shifa, N. A., & Lestari, N. E. (2024). Hubungan Burnout Syndrome Dengan Kualitas Tidur Perawat Caregiver Program Ij-Epa (Indonesia Japan-Economic Partnership Agreement) Tahun 2023. Jurnal Intelek Dan Cendikiawan Nusantara, 1(1), 654–662.

Lv, J.-C., & Zhang, L.-X. (2019). Prevalence and Disease Burden of Chronic Kidney Disease. In B.-C. Liu, H.-Y. Lan, & L.-L. Lv (Eds.), Renal Fibrosis: Mechanisms and Therapies (pp. 3–15). Springer. https://doi.org/10.1007/978-981-13-8871-2_1

Maesaroh, M., Waluyo, A., & Jumaiyah, W. (2020). Faktor-Faktor Yang Berhubungan Dengan Terjadinya Fatigue Pada Pasien Hemodialisis. Syntax Literate ; Jurnal Ilmiah Indonesia, 5(4), 110–120. https://doi.org/10.36418/syntax-literate.v5i4.1074

Mageswari dan Shaji. (2024). Prevalence, Associating factors and Impact of fatigue—A Systematic critical review on maintenance. African Journal of Bilogical Sciences, 6(10). https://doi.org/10.48047/AFJBS.6.10.2024.6238-6258

Maruyama, Y., Nakayama, M., Ueda, A., Miyazaki, M., & Yokoo, T. (2021). Comparisons of fatigue between dialysis modalities: A cross-sectional study. PLOS ONE, 16(2), e0246890. https://doi.org/10.1371/journal.pone.0246890

Mathis, B. J. (2021). The Intricate Web of Fatigue in Women. Women, 1(4), Article 4. https://doi.org/10.3390/women1040023

Mohanram, K. M., & Shaji, H. (2024). Prevalence, Associating factors and Impact of fatigue—A Systematic critical review on maintenance Hemodialysis patients. African Journal of Biological Sciences, 6(10).

Muliani, R., Muslim, A. R., & Abidin, I. (2021). Intradialytic Exercise: Flexibility terhadap Skor Fatigue pada Pasien Penyakit Ginjal Kronis yang Menjalani Hemodialisis. Journal of Medicine and Health, 3(2), Article 2. https://doi.org/10.28932/jmh.v3i2.3147

Muz, G., & Taşcı, S. (2017). Effect of aromatherapy via inhalation on the sleep quality and fatigue level in people undergoing hemodialysis. Applied Nursing Research: ANR, 37, 28–35. https://doi.org/10.1016/j.apnr.2017.07.004

Nurfajri, Q. A. F., Murtaqib, M., & Widayati, N. (2022). Literature Review Kejadian Depresi Pasien Gagal Ginjal Kronis yang Menjalani Terapi Hemodialisis. Jurnal Keperawatan, 7(2), Article 2. https://doi.org/10.32668/jkep.v7i2.849

Ouyang, Q., Yang, F., Wu, H., Tang, S., Peng, X., Li, Y., & Wang, J. (2023). The Effects of Dialysis Modality and Emotional Distress on Fatigue in Patients Undergoing Dialysis. Blood Purification, 52(9–10), 751–758. https://doi.org/10.1159/000532058

Patimah, S., Kusumajaya, H., & Faizal, K. M. (2024). Faktor-faktor yang Berhubungan dengan Fatigue pada Pasien Gagal Ginjal Kronis yang Menjalani Hemodialisis di Rumah Sakit Umum Daerah Depati Bahrin Sungailiat Tahun 2024. Jurnal Kesehatan Tambusai, 5(4), 11003–11012. https://doi.org/10.31004/jkt.v5i4.31920

Picariello, F., Norton, S., Moss-Morris, R., Macdougall, I. C., & Chilcot, J. (2020). A prospective study of fatigue trajectories among in-centre haemodialysis patients. British Journal of Health Psychology, 25(1), 61–88. https://doi.org/10.1111/bjhp.12395

Prastiwi, F. (2021). Analisis Faktor yang Berhubungan dengan Kelelahan pada Pasien Gagal Ginjal Kronik yang Menjalani Hemodialisis di RSU Yarsi Pontianak [Magister, Universitas Brawijaya]. http://repository.ub.ac.id/id/eprint/184615/

Prastiwi, F., Wihastuti, T., & Ismail, D. (2021). Factors Associated with Fatigue in Chronic Kidney Disease Patients Undergoing Hemodialysis: A Systematic Review. Jurnal Kedokteran Brawijaya, 31, 12. https://doi.org/10.21776/ub.jkb.2021.031.04.12

Pratiwi, S. D., Hamzah, A., Erlina, L., & Setiawan, A. (2024). Hubungan Lama menjalani Hemodialisa dengan Kelelahan Pasien Chronic Kidney Disease. Jurnal Keperawatan Indonesia Florence Nightingale, 4(2), Article 2. https://doi.org/10.34011/jkifn.v4i2.2632

Qiao, X., Zhan, Y., Li, L., & Cui, R. (2024). Development and validation of a nomogram to estimate fatigue probability in hemodialysis patients. Renal Failure, 46(2), 2396460. https://doi.org/10.1080/0886022X.2024.2396460

Sakiqi, J., Vasilopoulos, G., Koutelekos, I., Polikandrioti, M., Dousis, E., Pavlatou, N., Kalogianni, A., Tsirigotis, S., & Gerogianni, G. (2022). Depression Among Hemodialysis Patients: Related Factors and the Impact of Insomnia and Fatigue. Cureus, 14(5). https://doi.org/10.7759/cureus.25254

Santoso, D., Sawiji, S., Oktantri, H., & Septiwi, C. (2022). Faktor-Faktor Yang Berhubungan Dengan Fatigue Pada Pasien Gagal Ginjal Kronik Yang Menjalani Hemodialisa Di Rsud Dr. Soedirman Kebumen. Jurnal Ilmiah Kesehatan Keperawatan, 18(1), Article 1. https://doi.org/10.26753/jikk.v18i1.799

Saragih. (2024). Gambaran Karakteristik Pasaien Gagaal Ginjal Kronis Stadium V yang Menjalaani Hemodialisis. Jurnal Ilmiah Sain Dan Teknologi, 15(1), 37–48.

Saraswati, N. L. G. I., & Lestari, N. K. Y. (2024). Tingkat Fatigue Pada Pasien Yang Menjalani Hemodialisis: Fatigue Level In Patients Undergoing Hemodialisis. Journal Nursing Research Publication Media (NURSEPEDIA), 3(2), Article 2. https://doi.org/10.55887/nrpm.v3i2.128

Shi, R., Zhu, J., Zhu, L., Zhao, W., Li, H., Chen, Q., Pan, H., & Wang, D. (2024). Exploring the Nexus Between Fatigue, Body Composition, and Muscle Strength in Hemodialysis Patients. European Journal of Medical Research, 29(1), 266. https://doi.org/10.1186/s40001-024-01852-1

Syafira, D. A., Prihati, D. R., & Aini, D. N. (2024). Hubungan Depresi Dengan Kelelahan Pada Pasien Yang Menjalani Hemodialisa. Citra Delima Scientific Journal of Citra Internasional Institute, 8(1), 1–7. https://doi.org/10.33862/citradelima.v8i1.393

Tsirigotis, S., Polikandrioti, M., Alikari, V., Dousis, E., Koutelekos, I., Toulia, G., Pavlatou, N., Panoutsopoulos, G. I., Leftheriotis, D., & Gerogianni, G. (2022). Factors Associated With Fatigue in Patients Undergoing Hemodialysis. Cureus, 14(3), e22994. https://doi.org/10.7759/cureus.22994

Xia, A., Meuleman, Y., Dekker, F., & Hoogeveen, E. (2024). Risk Factors and Potential Treatments for Fatigue in Patients with Advanced CKD: A Narrative Review. https://doi.org/10.20944/preprints202412.1188.v1

You, Q., Bai, D., Wu, C., Chen, H., Hou, C., & Gao, J. (2022). Prevalence and Risk Factors of Postdialysis Fatigue in Patients Under Maintenance Hemodialysis: A Systematic Review and Meta-Analysis. Asian Nursing Research, 16(5), 292–298. https://doi.org/10.1016/j.anr.2022.11.002

Zainurridha, Y. A., Sakinah, N. A., & Azari, A. A. (2021). Faktor-Faktor yang Mempengaruhi Kemampuan Kognitif Lansia. Jurnal Penelitian Kesehatan “SUARA FORIKES” (Journal of Health Research “Forikes Voice”), 12(3), Article 3. https://doi.org/10.33846/sf12314

Zhang, Y., Liu, Z., Zhang, L., Zhu, P., Wang, X., & Huang, Y. (2019). Association of living arrangements with depressive symptoms among older adults in China: A cross-sectional study. BMC Public Health, 19(1), 1017. https://doi.org/10.1186/s12889-019-7350-8

Zhao, R., Zhang, W., Sun, M., Yang, C., Liu, X., & Chen, C. (2024). Analysis of factors influencing the trajectory of fatigue in maintenance haemodialysis patients: A longitudinal study. International Urology and Nephrology. https://doi.org/10.1007/s11255-024-04129-y

Zheng, X.-Y., Zhang, Z.-H., Cheng, Y.-M., Yang, Q., Xu, B., Lai, B.-C., & Huang, L.-T. (2023). Factors Associated with Subgroups of Fatigue in Maintenance Hemodialysis Patients: A Cross-Sectional Study. Renal Failure, 45(1), 2221129. https://doi.org/10.1080/0886022X.2023.2221129




DOI: https://doi.org/10.26751/jikk.v16i1.2877

Refbacks

  • There are currently no refbacks.


Universitas Muhammadiyah Kudus
Jl. Ganesha Raya No. 1 Purwosari Kudus 59316
Tel/ Fax +62-291-437218

Whatsapp : wa.me/+6285117477445

Email : lppm@umku.ac.id

Jurnal Ilmu Keperawatan dan Kebidanan Indexed by:

                  

Creative Commons License
This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.