HUBUNGAN ASUPAN PROTEIN DENGAN KADAR GLUKOSA DARAH 2 JAM PASCA PUASA PADA PASIEN DIABETES MELITUS TIPE 2
Abstract
Latar belakang: Diabetes melitus saat ini masih menjadi masalah kesehatan yang perlu diperhatikan, karena morbiditas dan mortalitasnya setiap tahun mengalami peningkatan. Indonesia salah satu negara yang menduduki peringkat ke 7 dunia dengan pasien diabetes melitus. Tujuan: Menganalisis hubungan asupan protein dan kadar glukosa darah puasa pada pasien diabtetes melitus tipe 2. Metode: Paseien diabetes melitus tipe 2 dengan total 210 dalam penelitian cross sectional ini. Pasien yang mengikuti penelitian ini sesuai dengan kriteria inklusi yaitu berusia 20-60 tahun bertempat tinggal di Kabupaten Purbalingga dan Banjarnegara. Pasien yang menderita komplikasi dan menggunakan injeksi insulin tidak diikutsertkan penelitian. Asupan protein diperoleh dari hasil recall 24 jam dan kada glukosa darah 2 jam pasca puasa diperoleh dari sampel darah vena pasien dengan metode hexokinase. Analisis uji yang digunakan adalah uji regresi linear. Hasil: Usia rata-rata subjek adalah 52.7+5.2 tahun. Sebanyak 47.6% subjek penelitian DMT2 dengan overweight dan 14.7% obesitas. Asupan protein (r=-0.712;95%CI= 0.049-0.003;p=0.024).Usia (r=0.378;95%CI=0.014-2.812;p=0.031). Indeks Masa Tubuh (r= 0.478; 95% CI=3.748-432; p=0.032 Kesimpulan: Terdapat hubungan yang kuat dan signifikan asupan protein dengan kadar GD2JPP pada subjek diabetes melitus tipe 2.
Full Text:
PDFReferences
Basu A et al. 2021. Dietary Blueberry and Soluble Fiber Supplementation Reduces Risk of Gestational Diabetes in Women with Obesity in a Randomized Controlled Trial. J Nutr. PMID: 33693835.
Chen L, et al. 2023. Hight fiber diet ameliorates gut microbiota, serum metabolism and emotional mood in type 2 diabetes patients. Front cell infect Microbiol. PMID: 36794003.
Dalle D, et al. 2023. Protein intake and postprandial hyperglycemia in children and adolescent with type 1 diabetes mellitus, a pilot study. Diabetes Metab Syndr. PMID 36905921.
Dambha-Miller H, et al. 2020. Behavior change, weight loss and remission on type 2 diabetes: a community-based prospective cohort study. Diabet Med. PMID: 31479535.
Evans M et al. 2019. Dietary protein affect both the dose and pattern of insulin delivery required to achive postprandial euglycaemia in type 1 diabetes: a randomized trial. Diabet Med. PMID 30537305.
Gardner CD et al. 2022. Effect of a ketogenic diet versus Mediterranean diet on glycated hemoglobin in individuals with prediabetes and type 2 diabetes mellitus:The interventional Keto_Med randomized crossover trial. Am J Clin Nutr. PMID35641199.
Gibbon C, et al. 2021. Effect of oral semaglutide on energy intake, food preference, appetite, control of eating and body weight in subjects with type 2 diabetes. Diabetes Obes Metab. PMID: 33184979.
Gulsin GS, et al. 2020. Effect of Low Energy Diet or Exercise on Cardiovascular function in working aged adults with type 2 diabetes: A prospective, Randomized, Open Label, Blinded end point Trial. Diabetes Care. PMID:32220917.
Hansen CD et al. 2023. Effect of Calorie-Unrestricted Low-Carbohydrate, High-Fat Diet Versus High-Carbohidrate, Low-Fat Diet on Type 2 Diabetes and Nonalcoholic Fatty Liver Disease: A Randomized Controlled Trial. Ann Intern Med. PMID: 36508737.
Harray AJ, et al. 2022. Effext of dietary Fat and protein on glucoregulatory hormones in Adolescents and young adults with type 1 Diabetes. J Clin Endocrinol Metab. PMID: 34410410.
Heise T, et al. 2023. Tizepatide Reduce Appetite, Energy Intake, and Fat Mass in People with type 2 diabetes. Diabetes Care. PMID: 36857477.
International Diabetes Federation. (2019). IDF Diabetes Atlas Seventh Edition. www.diabetesatlas.org. ISBN: 978-2-930229-81-2
Kementerian Kesehatan RI. (2018). Riset Kesehatan Dasar. Jakarta: Badan Penelitian dan Pengembangan Kesehatan Kementrian Republik Indonesia.
Mahjabeen W, et al. 2022. Role of resveratrol supplementation in regulation of glucose hemostasis, inflammation and oxidative stress in patients with diabetes mellitus type 2: a randomized, placebo-controlled trial. Complement Ther Med. PMID: 35240291.
Miller EG, et al. 2021. Effect of whey protein plus vitamin D supplementation combined with progressive resistance training on glycaemic contro, body composition, muscle function and cardiometabolic risk factors in middle-aged and older overweight/obese adults with type 2 diabetes A24 week randomized controlled trial. Diabetas Obes Metab. PMID: 33369020.
Mu L, et al. 2022. Effect of sodium reduction based on the DASH diet on blood pressure in hypertensive patients with type 2 diabetes. Nutr Hosp. PMID:35388704.
Parks S, et al. 2021.The Impact of Hayward green kiwifruit on dietary protein digestion and protein metabolism. Eur J Nutr. PMID: 32970234.
Peeters WM, e tal. 2023. Changes to insulin sensitivity in glucose clearance system and redox following dietary supplementation with a novel cysteine-rich protein: a pilot randomized controlled trial in humans with type 2 diabetes. Redox Biol. PMID: 37812879.
Soares ALS, et al. 2023. The influence of whey protein on muscle strength, glycemic control and functional tasks in older adult with type 2 Diabetes Mellitus in a Resistance Exercise Program: Randomized and Triple Blind Clinical Trial. Int J Environ Res Public Health. PMID:37239618.
Tettamanzi F et al. 2021. A High Protein Diet Is More Effective in Improving Insulin Resistance and Glycemic Variability Compared to a Mediterranean Diet-A Cross-Over Controlled Inpatient Dietary Study. Nutrients. PMID:34959931.
Ueki K , et al. 2021. Multivactorial intervention has a significant effect on diabetic kidney disease in patients with type 2 diabetes. Kidney Int. PMID: 32891604.
Yang X, et al. 2023. Effect of an Intermittent Calorie-restricted Diet on Type 2 Diabetes Remission: A Randomized Controlled Trial. J Clin Endocrinol Metab. PMID: 36515429.
Yuan Y, et al. 2023. The association between self monitoring of blood glucose and HbA1c in type 2 diabetes. Front endocrinol (Lausanne). PMID: 36824358.
Refbacks
- There are currently no refbacks.